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Exploring the binding sites and proton diffusion on insulin amyloid fibril surfaces by naphthol-based photoacid fluorescence and molecular simulations

The diffusion of protons along biological surfaces and the interaction of biological structures with water are fundamental areas of interest in biology and chemistry. Here, we examine the surface of insulin amyloid fibrils and follow the binding of small molecules (photoacids) that differ according...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Amdursky, Nadav, Rashid, M. Harunur, Stevens, Molly M., Yarovsky, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524688/
https://ncbi.nlm.nih.gov/pubmed/28740173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06030-4
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