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Structures of the Colossal RyR1 Calcium Release Channel

Ryanodine receptors (RyRs) are intracellular cation channels that mediate the rapid and voluminous release of Ca(2+) from the sarcoplasmic reticulum (SR) as required for excitation-contraction coupling in cardiac and skeletal muscle. Understanding of the architecture and gating of RyRs has advanced...

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Publicado en:Curr Opin Struct Biol
Main Authors: Clarke, Oliver B., Hendrickson, Wayne A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419430/
https://ncbi.nlm.nih.gov/pubmed/27687475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.09.002
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