Rapid Estradiol/ERα Signaling Enhances Aromatase Enzymatic Activity in Breast Cancer Cells

In situ estrogen production by aromatase conversion from androgens plays an important role in breast tumor promotion. Here, we show that 17β-estradiol (E(2)) can rapidly enhance aromatase enzymatic activity through an increase of aromatase protein phosphorylation in breast cancer cell lines. In vivo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Endocrinol
Hlavní autoři: Catalano, Stefania, Barone, Ines, Giordano, Cinzia, Rizza, Pietro, Qi, Hongyan, Gu, Guowei, Malivindi, Rocco, Bonofiglio, Daniela, Andò, Sebastiano
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2009
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419143/
https://ncbi.nlm.nih.gov/pubmed/19556341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0039
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky