Rapid Estradiol/ERα Signaling Enhances Aromatase Enzymatic Activity in Breast Cancer Cells

In situ estrogen production by aromatase conversion from androgens plays an important role in breast tumor promotion. Here, we show that 17β-estradiol (E(2)) can rapidly enhance aromatase enzymatic activity through an increase of aromatase protein phosphorylation in breast cancer cell lines. In vivo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Endocrinol
Egile Nagusiak: Catalano, Stefania, Barone, Ines, Giordano, Cinzia, Rizza, Pietro, Qi, Hongyan, Gu, Guowei, Malivindi, Rocco, Bonofiglio, Daniela, Andò, Sebastiano
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Endocrine Society 2009
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419143/
https://ncbi.nlm.nih.gov/pubmed/19556341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0039
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