A novel mechanism of cardioprotection through TNF-α-induced ectopic expression of keratins K8 and K18

The adult myocardium demonstrates a unique system of adaptation upon stress stimuli, in an effort to maintain its overall homeostasis. This compensatory mechanism remains a mystery(1). Tumor Necrosis Factor-α (TNF-α) is one of the major stress-induced pro-inflammatory cytokines that is up-regulated...

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發表在:Nat Med
Main Authors: Papathanasiou, Stamatis, Rickelt, Steffen, Soriano, Mageni, Schips, Tobias, Maier, Harald J., Davos, Constantinos H., Varela, Aimilia, Kaklamanis, Loukas, Scorrano, Luca, Mann, Douglas L., Capetanaki, Yassemi
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419049/
https://ncbi.nlm.nih.gov/pubmed/26280121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3925
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