Desmin mediates TNF-α–induced aggregate formation and intercalated disk reorganization in heart failure

We explored the involvement of the muscle-specific intermediate filament protein desmin in the model of tumor necrosis factor α (TNF-α)–induced cardiomyopathy. We demonstrate that in mice overexpressing TNF-α in the heart (α–myosin heavy chain promoter-driven secretable TNF-α [MHCsTNF]), desmin is m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Panagopoulou, Panagiota, Davos, Constantinos H., Milner, Derek J., Varela, Emily, Cameron, JoAnn, Mann, Douglas L., Capetanaki, Yassemi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396798/
https://ncbi.nlm.nih.gov/pubmed/18519735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710049
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados