Desmin and αB-crystallin interplay in the maintenance of mitochondrial homeostasis and cardiomyocyte survival

The association of desmin with the α-crystallin Β-chain (αΒ-crystallin; encoded by CRYAB), and the fact that mutations in either one of them leads to heart failure in humans and mice, suggests a potential compensatory interplay between the two in cardioprotection. To address this hypothesis, we inve...

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Veröffentlicht in:J Cell Sci
Hauptverfasser: Diokmetzidou, Antigoni, Soumaka, Elisavet, Kloukina, Ismini, Tsikitis, Mary, Makridakis, Manousos, Varela, Aimilia, Davos, Constantinos H., Georgopoulos, Spiros, Anesti, Vasiliki, Vlahou, Antonia, Capetanaki, Yassemi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087667/
https://ncbi.nlm.nih.gov/pubmed/27566162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.192203
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