Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains.
A common DNA binding and dimerization domain containing an apparent "helix-loop-helix" (HLH) structure was recognized recently in a number of regulatory proteins, including the E47 and E12 proteins that bind to the kappa E2 motif in immunoglobulin kappa gene enhancer. The effect of site-directed mut...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1990
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2112746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4722 |
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