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Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains.

A common DNA binding and dimerization domain containing an apparent "helix-loop-helix" (HLH) structure was recognized recently in a number of regulatory proteins, including the E47 and E12 proteins that bind to the kappa E2 motif in immunoglobulin kappa gene enhancer. The effect of site-di...

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Autors principals: Voronova, A, Baltimore, D
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC54189/
https://ncbi.nlm.nih.gov/pubmed/2112746
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