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Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes

During spermatogenesis, germ cells that fail to synapse their chromosomes or fail to undergo meiotic sex chromosome inactivation (MSCI) are eliminated via apoptosis during mid-pachytene. Previous work showed that Y-linked genes Zfy1 and Zfy2 act as ‘executioners’ for this checkpoint, and that wrongf...

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Xehetasun bibliografikoak
Argitaratua izan da:Hum Mol Genet
Egile Nagusiak: Vernet, Nadège, Mahadevaiah, Shantha K., de Rooij, Dirk G., Burgoyne, Paul S., Ellis, Peter J. I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418838/
https://ncbi.nlm.nih.gov/pubmed/27742779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw344
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