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Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes
During spermatogenesis, germ cells that fail to synapse their chromosomes or fail to undergo meiotic sex chromosome inactivation (MSCI) are eliminated via apoptosis during mid-pachytene. Previous work showed that Y-linked genes Zfy1 and Zfy2 act as ‘executioners’ for this checkpoint, and that wrongf...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5418838/ https://ncbi.nlm.nih.gov/pubmed/27742779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw344 |
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