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Paternal age effects on sperm FOXK1 and KCNA7 methylation and transmission into the next generation

Children of older fathers carry an increased risk for developing autism and other disorders. To elucidate the underlying mechanisms, we investigated the correlation of sperm DNA methylation with paternal age and its impact on the epigenome of the offspring. Methylation levels of nine candidate genes...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Atsem, Stefanie, Reichenbach, Juliane, Potabattula, Ramya, Dittrich, Marcus, Nava, Caroline, Depienne, Christel, Böhm, Lena, Rost, Simone, Hahn, Thomas, Schorsch, Martin, Haaf, Thomas, El Hajj, Nady
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418740/
https://ncbi.nlm.nih.gov/pubmed/28171595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw328
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