Paternal age effects on sperm FOXK1 and KCNA7 methylation and transmission into the next generation

Children of older fathers carry an increased risk for developing autism and other disorders. To elucidate the underlying mechanisms, we investigated the correlation of sperm DNA methylation with paternal age and its impact on the epigenome of the offspring. Methylation levels of nine candidate genes...

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Bibliographic Details
Published in:Hum Mol Genet
Main Authors: Atsem, Stefanie, Reichenbach, Juliane, Potabattula, Ramya, Dittrich, Marcus, Nava, Caroline, Depienne, Christel, Böhm, Lena, Rost, Simone, Hahn, Thomas, Schorsch, Martin, Haaf, Thomas, El Hajj, Nady
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418740/
https://ncbi.nlm.nih.gov/pubmed/28171595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw328
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