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Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR

Sarcomas differ from carcinomas in their mesenchymal origin. Therapeutic advancements have come slowly so alternative drugs and models are urgently needed. These studies report a new drug for sarcomas that simultaneously targets both tumor and tumor neovasculature. eBAT is a bispecific angiotoxin co...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Borgatti, Antonella, Koopmeiners, Joseph S., Sarver, Aaron L., Winter, Amber L., Stuebner, Kathleen, Todhunter, Deborah, Rizzardi, Anthony E., Henriksen, Jonathan C., Schmechel, Stephen, Forster, Colleen L., Kim, Jong-Hyuk, Froelich, Jerry, Walz, Jillian, Henson, Michael S., Breen, Matthew, Lindblad-Toh, Kerstin, Oh, Felix, Pilbeam, Kristy, Modiano, Jaime F., Vallera, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418099/
https://ncbi.nlm.nih.gov/pubmed/28193671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0637
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