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Chimeric Antigen Receptors: A Cell and Gene Therapy Perspective
Chimeric antigen receptors (CARs) are synthetic receptors that reprogram T lymphocytes to target chosen antigens. The targeting of CD19, a cell surface molecule expressed in the vast majority of leukemias and lymphomas, has been successfully translated in the clinic, earning CAR therapy a special di...
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| Udgivet i: | Mol Ther |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Gene & Cell Therapy
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417838/ https://ncbi.nlm.nih.gov/pubmed/28456379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.03.034 |
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