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Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences

Most implementations of mass spectrometry-based proteomics involve enzymatic digestion of proteins, expanding the analysis to multiple proteolytic peptides for each protein. Currently, there is no consensus of how to summarize peptides' abundances to protein concentrations, and such efforts are...

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Dades bibliogràfiques
Publicat a:Mol Cell Proteomics
Autors principals: Zhang, Bo, Pirmoradian, Mohammad, Zubarev, Roman, Käll, Lukas
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417831/
https://ncbi.nlm.nih.gov/pubmed/28302922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O117.067728
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