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Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences

Most implementations of mass spectrometry-based proteomics involve enzymatic digestion of proteins, expanding the analysis to multiple proteolytic peptides for each protein. Currently, there is no consensus of how to summarize peptides' abundances to protein concentrations, and such efforts are...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Zhang, Bo, Pirmoradian, Mohammad, Zubarev, Roman, Käll, Lukas
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417831/
https://ncbi.nlm.nih.gov/pubmed/28302922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O117.067728
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