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Rapid and Deep Human Proteome Analysis by Single-dimension Shotgun Proteomics

Multiparameter optimization of an LC-MS/MS shotgun proteomics experiment was performed without any hardware or software modification of the commercial instrument. Under the optimized experimental conditions, with a 50-cm-long separation column and a 4-h LC-MS run (including a 3-h optimized gradient)...

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Autors principals: Pirmoradian, Mohammad, Budamgunta, Harshavardhan, Chingin, Konstantin, Zhang, Bo, Astorga-Wells, Juan, Zubarev, Roman A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820943/
https://ncbi.nlm.nih.gov/pubmed/23878402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O113.028787
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