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Glucocorticoid Activity during Lung Maturation Is Essential in Mesenchymal and Less in Alveolar Epithelial Cells

Corticosteroid treatment is an established therapy for preterm infants, and germline inactivation of the glucocorticoid receptor (GR) gene in the mouse leads to respiratory failure and postnatal lethality. Although glucocorticoids have been thought to critically act in epithelial cells inducing the...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Habermehl, Daniel, Parkitna, Jan Rodriguez, Kaden, Sylvia, Brügger, Britta, Wieland, Felix, Gröne, Hermann-Josef, Schütz, Günther
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417239/
https://ncbi.nlm.nih.gov/pubmed/21659474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0380
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