Glucocorticoid Activity during Lung Maturation Is Essential in Mesenchymal and Less in Alveolar Epithelial Cells

Corticosteroid treatment is an established therapy for preterm infants, and germline inactivation of the glucocorticoid receptor (GR) gene in the mouse leads to respiratory failure and postnatal lethality. Although glucocorticoids have been thought to critically act in epithelial cells inducing the...

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Publicat a:Mol Endocrinol
Autors principals: Habermehl, Daniel, Parkitna, Jan Rodriguez, Kaden, Sylvia, Brügger, Britta, Wieland, Felix, Gröne, Hermann-Josef, Schütz, Günther
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2011
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417239/
https://ncbi.nlm.nih.gov/pubmed/21659474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0380
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