Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth

Mice carrying a hepatocyte-specific inactivation of the glucorticoid receptor (GR) gene show a dramatic reduction in body size. Growth hormone signaling mediated by the Stat5 transcription factors is impaired. We show that Stat5 proteins physically interact with GR and GR is present in vivo on Stat5...

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Detalhes bibliográficos
Main Authors: Tronche, François, Opherk, Christian, Moriggl, Richard, Kellendonk, Christoph, Reimann, Andreas, Schwake, Lukas, Reichardt, Holger M., Stangl, Katharina, Gau, Daniel, Hoeflich, Andreas, Beug, Hartmut, Schmid, Wolfgang, Schütz, Günther
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC374231/
https://ncbi.nlm.nih.gov/pubmed/15037546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.284704
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