Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth

Mice carrying a hepatocyte-specific inactivation of the glucorticoid receptor (GR) gene show a dramatic reduction in body size. Growth hormone signaling mediated by the Stat5 transcription factors is impaired. We show that Stat5 proteins physically interact with GR and GR is present in vivo on Stat5...

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Autors principals: Tronche, François, Opherk, Christian, Moriggl, Richard, Kellendonk, Christoph, Reimann, Andreas, Schwake, Lukas, Reichardt, Holger M., Stangl, Katharina, Gau, Daniel, Hoeflich, Andreas, Beug, Hartmut, Schmid, Wolfgang, Schütz, Günther
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2004
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC374231/
https://ncbi.nlm.nih.gov/pubmed/15037546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.284704
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