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Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth

Mice carrying a hepatocyte-specific inactivation of the glucorticoid receptor (GR) gene show a dramatic reduction in body size. Growth hormone signaling mediated by the Stat5 transcription factors is impaired. We show that Stat5 proteins physically interact with GR and GR is present in vivo on Stat5...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Tronche, François, Opherk, Christian, Moriggl, Richard, Kellendonk, Christoph, Reimann, Andreas, Schwake, Lukas, Reichardt, Holger M., Stangl, Katharina, Gau, Daniel, Hoeflich, Andreas, Beug, Hartmut, Schmid, Wolfgang, Schütz, Günther
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC374231/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15037546/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.284704
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