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Glucocorticoid Activity during Lung Maturation Is Essential in Mesenchymal and Less in Alveolar Epithelial Cells

Corticosteroid treatment is an established therapy for preterm infants, and germline inactivation of the glucocorticoid receptor (GR) gene in the mouse leads to respiratory failure and postnatal lethality. Although glucocorticoids have been thought to critically act in epithelial cells inducing the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Habermehl, Daniel, Parkitna, Jan Rodriguez, Kaden, Sylvia, Brügger, Britta, Wieland, Felix, Gröne, Hermann-Josef, Schütz, Günther
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417239/
https://ncbi.nlm.nih.gov/pubmed/21659474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0380
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