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Endoplasmic Reticulum (ER) Stress in Cumulus-Oocyte Complexes Impairs Pentraxin-3 Secretion, Mitochondrial Membrane Potential (ΔΨm), and Embryo Development

Fatty acids such as palmitic acid at high levels are known to induce endoplasmic reticulum (ER) stress and lipotoxicity in numerous cell types and thereby contribute to cellular dysfunctions in obesity. To understand the impact of high fatty acids on oocytes, ER stress and lipotoxicity were induced...

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Vydáno v:Mol Endocrinol
Hlavní autoři: Wu, Linda L., Russell, Darryl L., Norman, Robert J., Robker, Rebecca L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417137/
https://ncbi.nlm.nih.gov/pubmed/22383462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1362
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