Targeting the tumour microenvironment with an enzyme-responsive drug delivery system for the efficient therapy of breast and pancreatic cancers

The development of novel therapeutic strategies allowing the destruction of tumour cells while sparing healthy tissues is one of the main challenges of cancer chemotherapy. Here, we report on the design and antitumour activity of a low-molecular-weight drug delivery system programmed for the selecti...

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Udgivet i:Chem Sci
Main Authors: Renoux, Brigitte, Raes, Florian, Legigan, Thibaut, Péraudeau, Elodie, Eddhif, Balkis, Poinot, Pauline, Tranoy-Opalinski, Isabelle, Alsarraf, Jérôme, Koniev, Oleksandr, Kolodych, Sergii, Lerondel, Stéphanie, Le Pape, Alain, Clarhaut, Jonathan, Papot, Sébastien
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2017
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417048/
https://ncbi.nlm.nih.gov/pubmed/28507714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc00472a
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