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Detection of Aberrant TERT Promoter Methylation by Combined Bisulfite Restriction Enzyme Analysis for Cancer Diagnosis

Aberrant CpG dinucleotide methylation in a specific region of the telomerase reverse transcriptase (TERT) promoter is associated with increased TERT mRNA levels and malignancy in several cancer types. However, routine screening of this region to aid cancer diagnosis can be challenging because i) sev...

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Bibliografiske detaljer
Udgivet i:J Mol Diagn
Main Authors: Lee, Seungjae, Borah, Sumit, Bahrami, Armita
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417004/
https://ncbi.nlm.nih.gov/pubmed/28284778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2017.01.003
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