Phosphatidylinositol 3-Kinase-Binding Protein, PI3KAP/XB130, Is Required for cAMP-induced Amplification of IGF Mitogenic Activity in FRTL-5 Thyroid Cells

We previously demonstrated that long-term pretreatment of rat FRTL-5 thyroid cells with TSH or cAMP-generating reagents potentiated IGF-I-dependent DNA synthesis. Under these conditions, cAMP treatment increased tyrosine phosphorylation of a 125-kDa protein (p125) and its association with a p85 regu...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Endocrinol
Main Authors: Yamanaka, Daisuke, Akama, Takeshi, Fukushima, Toshiaki, Nedachi, Taku, Kawasaki, Chie, Chida, Kazuhiro, Minami, Shiro, Suzuki, Koichi, Hakuno, Fumihiko, Takahashi, Shin-Ichiro
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2012
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416991/
https://ncbi.nlm.nih.gov/pubmed/22496359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1349
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker