Direct Regulation of the Proglucagon Gene by Insulin, Leptin, and cAMP in Embryonic versus Adult Hypothalamic Neurons

The proglucagon gene is expressed not only in the pancreas and intestine but also in the hypothalamus. Proglucagon-derived peptides have emerged as potential regulators of energy homeostasis. Whether leptin, insulin, or cAMP activation controls proglucagon gene expression in the hypothalamus is not...

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Опубликовано в: :Mol Endocrinol
Главные авторы: Dalvi, Prasad S., Erbiceanu, Frederick D., Irwin, David M., Belsham, Denise D.
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2012
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416985/
https://ncbi.nlm.nih.gov/pubmed/22669740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1049
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