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Direct Regulation of the Proglucagon Gene by Insulin, Leptin, and cAMP in Embryonic versus Adult Hypothalamic Neurons

The proglucagon gene is expressed not only in the pancreas and intestine but also in the hypothalamus. Proglucagon-derived peptides have emerged as potential regulators of energy homeostasis. Whether leptin, insulin, or cAMP activation controls proglucagon gene expression in the hypothalamus is not...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Dalvi, Prasad S., Erbiceanu, Frederick D., Irwin, David M., Belsham, Denise D.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416985/
https://ncbi.nlm.nih.gov/pubmed/22669740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1049
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