20-HETE Induces Hyperglycemia through the cAMP/PKA-PhK-GP Pathway

We previously generated cytochrome P450 4F2 (CYP4F2) transgenic mice and showed high 20-hydroxyeicosatetraenoic acid (20-HETE) production, which resulted in an elevation of blood pressure. However, it was unclear whether 20-HETE affected glucose metabolism. We measured fasting plasma glucose, insuli...

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Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Lai, Guangrui, Wu, Jingjing, Liu, Xiaoliang, Zhao, Yanyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2012
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416963/
https://ncbi.nlm.nih.gov/pubmed/22918876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1139
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