Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice

The zinc finger protein CTCF has been invoked in establishing boundaries between genes, thereby controlling spatial and temporal enhancer activities. However, there is limited genetic evidence to support the concept that these boundaries restrict the search space of enhancers. We have addressed this...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Lee, Hye Kyung, Willi, Michaela, Wang, Chaochen, Yang, Chul Min, Smith, Harold E., Liu, Chengyu, Hennighausen, Lothar
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Genomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416830/
https://ncbi.nlm.nih.gov/pubmed/28334928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx185
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker