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Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation

Cytokines utilize the transcription factor STAT5 to control cell-specific genes at a larger scale than universal genes, with a mechanistic explanation yet to be supplied. Genome-wide studies have identified putative STAT5-based mammary-specific and universal enhancers, an opportunity to investigate...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Willi, Michaela, Yoo, Kyung Hyun, Wang, Chaochen, Trajanoski, Zlatko, Hennighausen, Lothar
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137441/
https://ncbi.nlm.nih.gov/pubmed/27694626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw844
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