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Annealing helicase HARP closes RPA-stabilized DNA bubbles non-processively
We investigate the mechanistic nature of the Snf2 family protein HARP, mutations of which are responsible for Schimke immuno-osseous dysplasia. Using a single-molecule magnetic tweezers assay, we construct RPA-stabilized DNA bubbles within torsionally constrained DNA to investigate the annealing act...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5416776/ https://ncbi.nlm.nih.gov/pubmed/28334870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx147 |
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