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The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA

HepA-related protein (HARP) (also known as SMARCAL1) is an ATP-driven annealing helicase that catalyzes the formation of dsDNA from complementary Replication protein A (RPA)-bound ssDNA. Here we find that HARP contains a conserved N-terminal motif that is necessary and sufficient for binding to RPA....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yusufzai, Timur, Kong, Xiangduo, Yokomori, Kyoko, Kadonaga, James T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764493/
https://ncbi.nlm.nih.gov/pubmed/19793863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1831509
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