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TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway
Mechanisms regulating the transition of mammary epithelial cells (MECs) to mammary stem cells (MaSCs) and to tumor-initiating cells (TICs) have not been entirely elucidated. The p53 family member, p63, is critical for mammary gland development and contains transactivation domain isoforms, which have...
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| Gepubliceerd in: | Oncogene |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5415945/ https://ncbi.nlm.nih.gov/pubmed/27869165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.388 |
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