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DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target
R.SwaI, a Type IIP restriction endonuclease, recognizes a palindromic eight base pair (bp) symmetric sequence, 5΄-ATTTAAAT-3΄, and cleaves that target at its center to generate blunt-ended DNA fragments. Here, we report three crystal structures of SwaI: unbound enzyme, a DNA-bound complex with calci...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5415892/ https://ncbi.nlm.nih.gov/pubmed/28180307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1200 |
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