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The KEAP1–NRF2 System in Cancer

Cancer cells first adapt to the microenvironment and then propagate. Mutations in tumor suppressor genes or oncogenes are frequently found in cancer cells. Comprehensive genomic analyses have identified somatic mutations and other alterations in the KEAP1 or NRF2 genes and in well-known tumor suppre...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Taguchi, Keiko, Yamamoto, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415577/
https://ncbi.nlm.nih.gov/pubmed/28523248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2017.00085
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