A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation

Mammalian limb development is driven by the integrative input from several signaling pathways; a failure to receive or a misinterpretation of these signals results in skeletal defects. The brachydactylies, a group of overlapping inherited human hand malformation syndromes, are mainly caused by mutat...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Bernatik, Ondrej, Radaszkiewicz, Tomasz, Behal, Martin, Dave, Zankruti, Witte, Florian, Mahl, Annika, Cernohorsky, Nicole H., Krejci, Pavel, Stricker, Sigmar, Bryja, Vitezslav
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415574/
https://ncbi.nlm.nih.gov/pubmed/28523267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00047
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