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Hygromycin B Hypersensitive (hhy) Mutants Implicate an Intact Trans-Golgi and Late Endosome Interface in Efficient Tor1 Vacuolar Localization and TORC1 Function
S. cerevisiae vacuoles are functionally analogous to mammalian lysosomes. Both also serve as physical platforms for Tor Complex 1 (TORC1) signal transduction, the master regulator of cellular growth and proliferation. Hygromycin B is a eukaryotic translation inhibitor. We recently reported on hygrom...
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| Publicado no: | Curr Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5415440/ https://ncbi.nlm.nih.gov/pubmed/27812735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-016-0660-9 |
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