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Hygromycin B Hypersensitive (hhy) Mutants Implicate an Intact Trans-Golgi and Late Endosome Interface in Efficient Tor1 Vacuolar Localization and TORC1 Function
S. cerevisiae vacuoles are functionally analogous to mammalian lysosomes. Both also serve as physical platforms for Tor Complex 1 (TORC1) signal transduction, the master regulator of cellular growth and proliferation. Hygromycin B is a eukaryotic translation inhibitor. We recently reported on hygrom...
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| Pubblicato in: | Curr Genet |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5415440/ https://ncbi.nlm.nih.gov/pubmed/27812735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-016-0660-9 |
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