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Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae

The vacuole of Saccharomyces cerevisiae has been a seminal model for studies of lysosomal trafficking, biogenesis, and function. Several yeast mutants defective in such vacuolar events have been unable to grow at low levels of hygromycin B, an aminoglycoside antibiotic. We hypothesized that such sev...

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Bibliografiske detaljer
Main Authors: Banuelos, M. G., Moreno, D. E., Olson, D. K., Nguyen, Q., Ricarte, F., Aguilera-Sandoval, C. R., Gharakhanian, Editte
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886664/
https://ncbi.nlm.nih.gov/pubmed/20043226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-009-0285-3
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