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A New Strategy for Selective Targeting of Progesterone Receptor With Passive Antagonists
Currently available progesterone (P4) receptor (PR) antagonists, such as mifepristone (RU486), lack specificity and display partial agonist properties, leading to potential drawbacks in their clinical use. Recent x-ray crystallographic studies have identified key contacts involved in the binding of...
Shranjeno v:
| izdano v: | Mol Endocrinol |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Endocrine Society
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5415273/ https://ncbi.nlm.nih.gov/pubmed/23579486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1328 |
| Oznake: |
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