A New Strategy for Selective Targeting of Progesterone Receptor With Passive Antagonists

Currently available progesterone (P4) receptor (PR) antagonists, such as mifepristone (RU486), lack specificity and display partial agonist properties, leading to potential drawbacks in their clinical use. Recent x-ray crystallographic studies have identified key contacts involved in the binding of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Khan, Junaid A., Tikad, Abdellatif, Fay, Michel, Hamze, Abdallah, Fagart, Jérôme, Chabbert-Buffet, Nathalie, Meduri, Geri, Amazit, Larbi, Brion, Jean-Daniel, Alami, Mouad, Lombès, Marc, Loosfelt, Hugues, Rafestin-Oblin, Marie-Edith
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415273/
https://ncbi.nlm.nih.gov/pubmed/23579486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1328
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados