Composite biomarkers defined by multiparametric immunofluorescence analysis identify ALK-positive adenocarcinoma as a potential target for immunotherapy

Anaplastic lymphoma kinase (ALK) inhibitors have been successfully developed for non-small cell lung carcinoma (NSCLC) displaying chromosomal rearrangements of the ALK gene, but unfortunately resistance invariably occurs. Blockade of the PD-1-PD-L1/2 inhibitory pathway constitutes a breakthrough for...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Roussel, Hélène, De Guillebon, Eléonore, Biard, Lucie, Mandavit, Marion, Gibault, Laure, Fabre, Elisabeth, Antoine, Martine, Hofman, Paul, Beau-Faller, Michèle, Blons, Hélène, Danel, Claire, Barthes, Françoise Le Pimpec, Gey, Alain, Granier, Clémence, Wislez, Marie, Laurent-Puig, Pierre, Oudard, Stéphane, Bruneval, Patrick, Badoual, Cécile, Cadranel, Jacques, Tartour, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414864/
https://ncbi.nlm.nih.gov/pubmed/28507793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1286437
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