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Early Embryonic Androgen Exposure Induces Transgenerational Epigenetic and Metabolic Changes
Androgen excess is a central feature of polycystic ovary syndrome (PCOS), which affects 6% to 10% of young women. Mammals exposed to elevated androgens in utero develop PCOS-like phenotypes in adulthood, suggesting fetal origins of PCOS. We hypothesize that excess androgen exposure during early embr...
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| Pubblicato in: | Mol Endocrinol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Endocrine Society
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5414805/ https://ncbi.nlm.nih.gov/pubmed/24992182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1042 |
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