Early Embryonic Androgen Exposure Induces Transgenerational Epigenetic and Metabolic Changes

Androgen excess is a central feature of polycystic ovary syndrome (PCOS), which affects 6% to 10% of young women. Mammals exposed to elevated androgens in utero develop PCOS-like phenotypes in adulthood, suggesting fetal origins of PCOS. We hypothesize that excess androgen exposure during early embr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Endocrinol
Prif Awduron: Xu, Ning, Chua, Angela K., Jiang, Hong, Liu, Ning-Ai, Goodarzi, Mark O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414805/
https://ncbi.nlm.nih.gov/pubmed/24992182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1042
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