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Phoenixin Activates Immortalized GnRH and Kisspeptin Neurons Through the Novel Receptor GPR173

Reproductive function is coordinated by kisspeptin (Kiss) and GnRH neurons. Phoenixin-20 amide (PNX) is a recently described peptide found to increase GnRH-stimulated LH secretion in the pituitary. However, the effects of PNX in the hypothalamus, the putative signaling pathways, and PNX receptor hav...

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Vydáno v:Mol Endocrinol
Hlavní autoři: Treen, Alice K., Luo, Vicky, Belsham, Denise D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414621/
https://ncbi.nlm.nih.gov/pubmed/27268078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2016-1039
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