The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling

BACKGROUND: Renal cell carcinomas (RCCs) display broad resistance against conventional radio- and chemotherapies, which is due at least in part to impairments in both extrinsic and intrinsic apoptotic pathways. One important anti-apoptotic factor that is strongly overexpressed in RCCs and known to i...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Commun Signal
Auteurs principaux: Toth, Csaba, Funke, Sarah, Nitsche, Vanessa, Liverts, Anna, Zlachevska, Viktoriya, Gasis, Marcia, Wiek, Constanze, Hanenberg, Helmut, Mahotka, Csaba, Schirmacher, Peter, Heikaus, Sebastian
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414156/
https://ncbi.nlm.nih.gov/pubmed/28464919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0170-5
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