A Critical Role for the Anti-apoptotic Protein ARC (Apoptosis Repressor with CARD) in Hypoxia-Induced Pulmonary Hypertension

BACKGROUND: Pulmonary hypertension (PH) is a lethal syndrome associated with the pathogenic remodeling of the pulmonary vasculature and the emergence of apoptosis-resistant cells. ARC (Apoptosis Repressor with Caspase Recruitment Domain) is an inhibitor of multiple forms of cell death known to be ab...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Zaiman, Ari L, Damico, Rachel, Thoms-Chesley, Alan, Files, D Clark, Kesari, Priya, Johnston, Laura, Swaim, Mara, Mozammel, Shehzin, Myers, Alan C, Halushka, Marc, El-Haddad, Hasim, Shimoda, Larissa A, Peng, Chang-Fu, Hassoun, Paul M, Champion, Hunter C, Kitsis, Richard N, Crow, Michael T
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583146/
https://ncbi.nlm.nih.gov/pubmed/22082675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.034512
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