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Depression-like episodes in mice harboring mtDNA deletions in paraventricular thalamus
Depression is a common debilitating human disease whose etiology has defied decades of research. A critical bottleneck is the difficulty in modeling depressive episodes in animals. Here, we show that a transgenic mouse with chronic forebrain expression of a dominant negative mutant of Polg1, a mitoc...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Psychiatry |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5414076/ https://ncbi.nlm.nih.gov/pubmed/26481320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.156 |
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