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A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density

In macromolecular crystallography, the rigorous detection of changed states (for example, ligand binding) is difficult unless signal is strong. Ambiguous (‘weak' or ‘noisy') density is experimentally common, since molecular states are generally only fractionally present in the crystal. Exi...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Pearce, Nicholas M., Krojer, Tobias, Bradley, Anthony R., Collins, Patrick, Nowak, Radosław P., Talon, Romain, Marsden, Brian D., Kelm, Sebastian, Shi, Jiye, Deane, Charlotte M., von Delft, Frank
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413968/
https://ncbi.nlm.nih.gov/pubmed/28436492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15123
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