Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer’s Disease

Current hypotheses and theories regarding the pathogenesis of Alzheimer’s disease (AD) heavily implicate brain insulin resistance (IR) as a key factor. Despite the many well-validated metrics for systemic IR, the absence of biomarkers for brain-specific IR represents a translational gap that has hin...

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Bibliographic Details
Published in:Front Aging Neurosci
Main Authors: Mullins, Roger J., Diehl, Thomas C., Chia, Chee W., Kapogiannis, Dimitrios
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413582/
https://ncbi.nlm.nih.gov/pubmed/28515688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00118
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