Characterization of an Abiraterone Ultraresponsive Phenotype in Castration-Resistant Prostate Cancer Patient-Derived Xenografts

PURPOSE: To identify the molecular signature associated with abiraterone acetate (AA) response and mechanisms underlying AA resistance in castration-resistant prostate cancer patient-derived xenografts (PDXs). EXPERIMENTAL DESIGN: SCID mice bearing LuCaP 136CR, 77CR, 96CR, and 35CR PDXs were treated...

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Publicado no:Clin Cancer Res
Principais autores: Lam, Hung-Ming, McMullin, Ryan, Nguyen, Holly M., Coleman, Ilsa, Gormley, Michael, Gulati, Roman, Brown, Lisha G., Holt, Sarah K., Li, Weimin, Ricci, Deborah S., Verstraeten, Karin, Thomas, Shibu, Mostaghel, Elahe A., Nelson, Peter S., Vessella, Robert L., Corey, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413408/
https://ncbi.nlm.nih.gov/pubmed/27993966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2054
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