Characterization of an Abiraterone Ultraresponsive Phenotype in Castration-Resistant Prostate Cancer Patient-Derived Xenografts

PURPOSE: To identify the molecular signature associated with abiraterone acetate (AA) response and mechanisms underlying AA resistance in castration-resistant prostate cancer patient-derived xenografts (PDXs). EXPERIMENTAL DESIGN: SCID mice bearing LuCaP 136CR, 77CR, 96CR, and 35CR PDXs were treated...

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Опубликовано в: :Clin Cancer Res
Главные авторы: Lam, Hung-Ming, McMullin, Ryan, Nguyen, Holly M., Coleman, Ilsa, Gormley, Michael, Gulati, Roman, Brown, Lisha G., Holt, Sarah K., Li, Weimin, Ricci, Deborah S., Verstraeten, Karin, Thomas, Shibu, Mostaghel, Elahe A., Nelson, Peter S., Vessella, Robert L., Corey, Eva
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413408/
https://ncbi.nlm.nih.gov/pubmed/27993966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2054
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