Sclerostin antibody administration converts bone lining cells into active osteoblasts

Sclerostin antibody (Scl-Ab) increases osteoblast activity, in part through increasing modeling-based bone formation on previously quiescent surfaces. Histomorphometric studies have suggested that this might occur through conversion of bone lining cells into active osteoblasts. However, direct data...

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Pubblicato in:J Bone Miner Res
Autori principali: Kim, Sang Wan, Lu, Yanhui, Williams, Elizabeth A., Lai, Forest, Lee, Ji Yeon, Enishi, Tetsuya, Balani, Deepak H., Ominsky, Michael S., Ke, Hua Zhu, Kronenberg, Henry M., Wein, Marc N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413385/
https://ncbi.nlm.nih.gov/pubmed/27862326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3038
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