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Selective Biological Responses of Phagocytes and Lungs to Purified Histones

Histones invoke strong proinflammatory responses in many different organs and cells. We assessed biological responses to purified or recombinant histones, using human and murine phagocytes and mouse lungs. H1 had the strongest ability in vitro to induce cell swelling independent of requirements for...

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Détails bibliographiques
Publié dans:J Innate Immun
Auteurs principaux: Fattahi, Fatemeh, Grailer, Jamison J., Lu, Hope, Dick, Rachel S., Parlett, Michella, Zetoune, Firas S., Nuñez, Gabriel, Ward, Peter A.
Format: Artigo
Langue:Inglês
Publié: S. Karger AG 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413366/
https://ncbi.nlm.nih.gov/pubmed/28171866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000452951
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